PSI - Issue 43

Available online at www.sciencedirect.com Available online at www.sciencedirect.com ScienceDirect Structural Integrity Procedia 00 (2022) 000 – 000 Available online at www.sciencedirect.com ScienceDirect Structural Integrity Procedia 00 (2022) 000 – 000

www.elsevier.com/locate/procedia www.elsevier.com/locate/procedia

ScienceDirect

Procedia Structural Integrity 43 (2023) 276–281

© 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under the responsibility of MSMF10 organizers. © 20 23 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Peer-review under the responsibility of MSMF10 organizers. Abstract C mputational modeling plays an imp rtant role in ass s ment of biomaterial structures, living tissue and their mechanic properties. Microstructure investigation of bone tissue needs high-level comp tational models based on μ -CT i ages. A crucial factor when creating a computational model is image processing using tissue segmentation. The most common method for segmentation is thresholding. Threshold value can influence the g ometry model and mechanical esponse in the bone tissue. One f the aims of th w rk is to determine and analyze the apparent m chanical behavior of m d bular trabecular b ne struc ure based on differe t thre hold value. Another aim f this study s to assess its influe ce on strain intensity from a local point of view, namely on one specific trabecula . Fifty-four computational models includ ng d tailed trab ular structure of mandible were created based on μ -CT images. The thresholding was observed to have a significant effect on mechanical behavior of the trabecular bone structure. © 20 23 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Peer-review under the responsibility of MSMF10 organizers. 10th International Conference on Materials Structure and Micromechanics of Fracture The influence of image processing of μ -CT images on mechanical behavior of mandibular trabecular bone structure using micro finite element method Apolena Šustková a * , Barbora Thomková a , Tomáš Zikmund b , Jozef Kaiser b , Marek Joukal c , Petr Marcián a a Faculty of Mechanical Engineering, Brno University of Technology, Technická 2896/2, Brno, 616 69, Czech Republic b CEITEC – Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, Brno , 612 00, Czech Republic c Department of Anatomy, Faculty of Medicine, Masaryk University, Kamenice 753/5, Brno, 625 00, Czech Republic Abstract Computational modeling plays an important role in assessment of biomaterial structures, living tissue and their mechanical properties. Microstructure investigation of bone tissue needs high-level computational models based on μ -CT images. A crucial factor when creating a computational model is image processing using tissue segmentation. The most common method for segmentation is thresholding. Threshold value can influence the geometry model and mechanical response in the bone tissue. One of the aims of the work is to determine and analyze the apparent mechanical behavior of mandibular trabecular bone structure based on different threshold value. Another aim of this study is to assess its influence on strain intensity from a local point of view, namely on one specific trabeculae. Fifty-four computational models including detailed trabecular structure of mandible were created based on μ -CT images. The thresholding was observed to have a significant effect on mechanical behavior of the trabecular bone structure. 10th International Conference on Materials Structure and Micromechanics of Fracture The influence of image processing of μ -CT images on mechanical behavior of mandibular trabecular bone structure using micro finite element method Apolena Šustková a * , Barbora Thomková a , Tomáš Zikmund b , Jozef Kaiser b , Marek Joukal c , Petr Marcián a a Facul y of Mechanical Engineering, Brno University of Technology, Technická 2896/2, Brno, 616 69, Czech Republic b CEITEC – C ntral Eur pea Institute of Technology, Brno University of Technology, Purkyňova 656/1 3, Brno , 612 00, Cze h Republic c Department of Anatomy, Faculty of Medicine, Masaryk University, Kamenice 753/5, Brno, 625 00, Czech Republic

Keywords: image processing; trabecular bone structure; thresholding ; µ -CT; FEM Keywords: image processing; trabecular bone structure; thresholding ; µ -CT; FEM

* Corresponding author. E-mail address: apolena.sustkova@vutbr.cz * Correspon ing author. E-mail address: apolena.sustkova@vutbr.cz

2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under the responsibility of MSMF10 organizers. 10.1016/j.prostr.2022.12.271 2452-3216 © 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under the responsibility of MSMF10 organizers. 2452-3216 © 2023 The Authors. Published by Elsevier B.V. This is an ope access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under the responsibility of MSMF10 organizers.

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