PSI - Issue 50

Available online at www.sciencedirect.com Available online at www.sciencedirect.com ScienceDirect Structural Integrity Procedia 00 (2022) 000 – 000 Available online at www.sciencedirect.com ScienceDirect Structural Integrity Procedia 00 (2022) 000 – 000

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ScienceDirect

Procedia Structural Integrity 50 (2023) 307–313

© 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0 ) Peer-review under responsibility of the scientific committee of the MRDMS 2022 organizers Abstract To create titanium-based bone implants, it is urgent to create bioactive coatings that ensure their rapid engraftment. The rate of fusion of Ti implants with bone tissue is significantly affected by the degree of implant surface modification based on changes in the relief or chemical composition of the surface layer, as well as a combination of these two approaches. In this work, we investigated the possibility of creating composite coatings with a two-level hierarchy of the surface topography at the micro- and nanolevels with bioactive and bactericidal properties that are promising for bone implantation. A technique for template electrochemical synthesis of a composite coating with directional control of the titanium surface structure based on titanium dioxide, silver, and hydroxyapatite was developed. Studies have shown that the TiO 2 /Ag composite coating with an island-like microstructure and a pore size of 5-20 nm has a significant cytological response and the ability to accelerate osteosynthesis. Thus, the developed biomaterial can be used to manufacture implants with improved biomedical properties for dentistry and orthopedics. © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of the scientific committee of MRDMS 2022 organizers . Keywords: Implant; template electrochemical synthesis; silver; titanium; titanium dioxide Creation of a bioactive coating on titanium with a two-level surface structure hierarchy at the nano- and micro-level promising for bone implantation E.G. Zemtsova a *, D.N. Sokolova a , L.A. Kozlova a , V.K. Kudymov a , A.N. Ponomaryova a , N.F. Morozov a , V.M. Smirnov a a Saint Petersburg State University, 198504, Universitetskiy Pr., 26, Saint Petersburg, Russian Federation Abstract To create titanium-based bone implants, it is urgent to create bioactive coatings that ensure their rapid engraftment. The rate of fusion of Ti implants with bone tissue is significantly affected by the degree of implant surface modification based on changes in the relief or chemical composition of the surface layer, as well as a combination of these two approaches. In this work, we investigated the possibility of creating composite coatings with a two-level hierarchy of the surface topography at the micro- and nanolevels with bioactive and bactericidal properties that are promising for bone implantation. A technique for template electrochemical synthesis of a composite coating with directional control of the titanium surface structure based on titanium dioxide, silver, and hydroxyapatite was developed. Studies have shown that the TiO 2 /Ag composite coating with an island-like microstructure and a pore size of 5-20 nm has a significant cytological response and the ability to accelerate osteosynthesis. Thus, the developed biomaterial can be used to manufacture implants with improved biomedical properties for dentistry and orthopedics. © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of the scientific committee of MRDMS 2022 organizers . Keywords: Implant; template electrochemical synthesis; silver; titanium; titanium dioxide 16th International Conference on Mechanics, Resource and Diagnostics of Materials and Structures (MRDMS 2022) Creation of a bioactive coating on titanium with a two-level surface structure hierarchy at the nano- and micro-level promising for bone implantation E.G. Zemtsova a *, D.N. Sokolova a , L.A. Kozlova a , V.K. Kudymov a , A.N. Ponomaryova a , N.F. Morozov a , V.M. Smirnov a a Saint Petersburg State University, 198504, Universitetskiy Pr., 26, Saint Petersburg, Russian Federation 16th International Conference on Mechanics, Resource and Diagnostics of Materials and Structures (MRDMS 2022)

* Corresponding author. Tel.:8 (812)428-40-33. E-mail address: ezimtsova@yandex.ru * Corresponding author. Tel.:8 (812)428-40-33. E-mail address: ezimtsova@yandex.ru

2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of the scientific committee of the MRDMS 2022 organizers 2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of the scientific committee of the MRDMS 2022 organizers

2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of the scientific committee of the MRDMS 2022 organizers 10.1016/j.prostr.2023.10.055