PSI - Issue 49

Available online at www.sciencedirect.com Structural Integrity Procedia 00 (2023) 000–000 Available online at www.sciencedirect.com ScienceDirect Structural Integrity Procedia 00 (2023) 000–000 Available online at www.sciencedirect.com ScienceDirect

www.elsevier.com/locate/procedia www.elsevier.com/locate/procedia

ScienceDirect

Procedia Structural Integrity 49 (2023) 51–58

© 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of ICMD3M 2023 organizers Abstract Since the 1990s, endovascular aortic aneurysm repair (EVAR) has become a common alternative to open surgery for the treatment of abdominal aortic aneurysms (AAAs). Despite being associated with faster recovery time and lower peri-operative mortality, EVAR procedures carry a number of limitations. In particular, EVAR has been noted to fail, or be deemed unfeasible, in cases where patients have severe arterial calcification presence. An accurate numerical simulation model of the procedure including consideration of patient-specific aortic calcification is important for determining the feasibility of EVAR for AAA patients prior to intervention. In addition, such a numerical simulationcanprovideunderstandingof the stress response of different regions of the aortic structure (neck, aneurysm, bifurcation, iliacs, and calcified tissue boundary) impacted during EVAR. In the present work, we introduce such a model by developing and analysing numerical simulations of EVAR intervention on 12 AAA patients. With this approach we can obtain insight into the likelihood of procedural success by comparing aortic peak wall stress (PWS) to the theoretical aortic wall strength, and we can investigate the impact of calcification presence on stress distribution throughout the aortic structure, during intervention. Furthermore, we discuss the relationship between the severity of calcification presence and the aortic PWS . © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of ICMD3M 2023 organizers Keywords: Calcification ꞏEndovascular aortic aneurysm repair ꞏNumerical simulation ꞏPeak wall stress ꞏRupture risk, Patient-specific Medical Devices: Materials, Mechanics and Manufacturing A patient-specific numerical model to assess the impact of calcification stress during endovascular aortic aneurysm repair S. McLennan a,b , G. Soulez b , H. Mohammadi b , M. Pfister c , S. Lessard b , R. Mongrain a * a Department of Mechanical Engineering, McGill University, Montreal, H3A 0C3, Canada b Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, H2X 0A9, Canada c Siemens Healthcare GmbH, Forchheim, Germany Abstract Since the 1990s, endovascular aortic aneurysm repair (EVAR) has become a common alternative to open surgery for the treatment of abdominal aortic aneurysms (AAAs). Despite being associated with faster recovery time and lower peri-operative mortality, EVAR procedures carry a number of limitations. In particular, EVAR has been noted to fail, or be deemed unfeasible, in cases where patients have severe arterial calcification presence. An accurate numerical simulation model of the procedure including consideration of patient-specific aortic calcification is important for determining the feasibility of EVAR for AAA patients prior to intervention. In addition, such a numerical simulationcanprovideunderstandingof the stress response of different regions of the aortic structure (neck, aneurysm, bifurcation, iliacs, and calcified tissue boundary) impacted during EVAR. In the present work, we introduce such a model by developing and analysing numerical simulations of EVAR intervention on 12 AAA patients. With this approach we can obtain insight into the likelihood of procedural success by comparing aortic peak wall stress (PWS) to the theoretical aortic wall strength, and we can investigate the impact of calcification presence on stress distribution throughout the aortic structure, during intervention. Furthermore, we discuss the relationship between the severity of calcification presence and the aortic PWS . © 2023 The Authors. Published by ELSEVIER B.V. Keywords: Calcification ꞏEndovascular aortic aneurysm repair ꞏNumerical simulation ꞏPeak wall stress ꞏRupture risk, Patient-specific Medical Devices: Materials, Mechanics and Manufacturing A patient-specific numerical model to assess the impact of calcification stress during endovascular aortic aneurysm repair S. McLennan a,b , G. Soulez b , H. Mohammadi b , M. Pfister c , S. Lessard b , R. Mongrain a * a Department of Mechanical Engineering, McGill University, Montreal, H3A 0C3, Canada b Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, H2X 0A9, Canada c Siemens Healthcare GmbH, Forchheim, Germany

Corresponding author. E-mail address: rosaire.mongrain@mcgill.ca Corresponding author. E-mail address: rosaire.mongrain@mcgill.ca

2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of ICMD3M 2023 organizers 2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of ICMD3M 2023 organizers

2452-3216 © 2023 The Authors. Published by ELSEVIER B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of ICMD3M 2023 organizers 10.1016/j.prostr.2023.10.009